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Excalia

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Excalia
Review Summary
Weight loss supplements and pharmaceutical drugs abound on the market these days. The rise in obesity accounts for some of this proliferation of weight loss aids, as well as consumer’s interest in losing weight and toning up in general. Excalia is a new pharmaceutical weigh loss drug geared toward addressing obesity in particular. It was created by OREXIGENTM Therapeutics, Inc., a neuroscience company, which is geared toward creating innovative tactical approaches to the management of obesity.

Ingredients At a Glance
Excalia contains - zonisamide SR and bupropion SR.

Ingredients in Focus
Excalia is currently undergoing clinical trails so it is not available at the present time. It is believed to be able to provide users with rapid weight loss. For instance, it helped those in the initial clinical trials lose %12 of their body fat. The active ingredients in this formula are zonisamide SR and bupropion SR; two elements which were not originally slatted for weight loss, however, Dr. Kishore Gadde of Duke University discovered the combinations potential weight loss abilities. Zonisamide SR, was originally used to treat seizure disorders; although how it achieves this affect is still not known. It was in these clinical trials that its ability to help augment weight loss was noticed.

The name bupropion SR may not be well known, however, this drug goes by other names that are more recognizable, such as Wellbutrin and Zyban; two antidepressants which a have been used to help individuals stop smoking. This drug was shown to help those who were both depressed and obese lose weight. This manufacturer hopes by combining these two drugs that the resulting medication will affectively address obesity from multiple avenues.

Diet Lifestyle
Obviously, pharmaceutical drugs have a place in treating weight loss, especially when individuals are suffering from chronic obesity that requires medical intervention and supervision. It is clear from all the data available that Excalia may eventually be proven to be able to help treat obesity. We are looking forward to seeing the results from the clinical trails when they are completed.

However, most pharmaceutical drugs and holistically based weight loss supplements are used in tandem with a healthy diet and a moderate fitness plan; both of which have been proven to be necessary to create long term and sustainable weight loss.

Positives
• May eventually be a treatment for obesity


Negatives
• Not yet approved
• When approved it will require medical supervision
• Not a cure


Final Thoughts
It is believed by this manufacturer that the clinical trials will prove that the drug combination used in Excalia will be able to directly affect the hypothalamus, which helps regulate appetite and energy output, as well as helping maintain body weight. This is reminiscent of the affect Hoodia, a holistically based weight loss product has on the brain.

Hoodia contains an element called “P57” which has been proven to be able to convince the brain that the stomach is full, even when it clearly is not, which effectively removes hunger from the weight loss equation.

Hoodia has been shown to work really well with other holistic weight loss agents, which means that it can be used part as a team to address weight loss form multiple avenues, similar to the concept use to develop Excalia. For instance, Hoodia works exceptionally well when it is teamed up with Advantra Z, an excellent thermogenic agent that effectively boosts metabolism and fat burning ability; and GTF Chromium, which can help convert sugar into energy before it becomes fat.

 

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Week of: Tue Mar 09th, 2010
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